In fact, TERT phosphorylation is shown to be necessary for telomerase activation. b Result of BETi on telomere regulation. BETi contend with acetylated histones with the binding for the BRD4 bromodomains releasing BRD4 from quick telomere, destabilizing telomere safety complicated Firm and decreasing Telomerase activity. The progressive shortening of telomere https://-jq-1researchstudies35689.bloggadores.com/31224481/jq-1-inhibition-of-brd4-an-overview