In this article, we demonstrate that conolidine, a pure analgesic alkaloid used in conventional Chinese medication, targets ACKR3, therefore furnishing further evidence of the correlation involving ACKR3 and soreness modulation and opening alternate therapeutic avenues with the therapy of chronic discomfort. Long-term discomfort is advanced, and it might take https://tomt790tla4.wikienlightenment.com/user