IntroductionTo investigate the effects of hepatic arterial infusion chemotherapy (HAIC) with or without systemic chemotherapy compared to systemic chemotherapy alone in patients with locally advanced hepatocellular carcinoma (HCC). MethodsFollowing a registered protocol (PROSPERO 2023 CRD42023386780 Available from: https://www. crd. https://www.lightemupsequences.com/flash-pick-Tiki-Luau-Shaped-Thank-You-Cards-Tropical-Hawaiian-Summer-Party-Thank-You-Note-Cards-with-Envelopes-Set-of-12-top-super