And finally, clonidine improves neuraxial opioids and, together with fentanyl, interacts within an additive way, which could lessen the dose of each part by 60% for postoperative analgesia. Could be offered as monotherapy or as adjunctive therapy with stimulants. The prolonged-launch isn't interchangeable with the fast-launch merchandise. For seniors: https://www.proleviate.com/post/the-new-pain-killer-conolidine