Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors in the central anxious system, conolidine modulates alternate molecular targets. A Science Advances review located that conolidine interacts While using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://titusmuzcf.blogs-service.com/70013513/the-ultimate-guide-to-alternative-natural-pain-relief-to-replace-traditional-painkillers